Benign Mesothelioma

Mesothelioma is a very dangerous type of cancer that up until know, the cure is still not found yet. However, like other cancer there is a time when mesothelioma cancer still in situ (a condition where mesothelioma has not become cancerous yet) or benign mesothelioma.

There is a difference between mesothelioma and benign mesothelioma. When it still not cancerous, this cancer usually does not has any relation with asbestos exposure. Benign mesothelioma usually associated with solitary fibrous tumor of pleura, it is a former neoplasm that referred to as benign fibrous pleural mesothelioma. The visceral or parietal pleura fibrous tumors are often have not relation with asbestos exposure, with pleural effusion as an exception. Most of these fibrous tumors are benign, although a malignant form does rarely occur.


Clubbing and osteoarthropathy are common benign mesothelioma symptoms that present in 20% to 50% of cases, compared to malignant mesothelioma that only count 6%. Hyponatremia attributed to inappropriate secretion of anti-diuretic hormone and hypoglycemia has been described. Surgery is an appropriate treatment that can cure it.

When see under microscope, benign mesothelioma tumors are well circumscribed fibromas with a variable collage-nous matrix containing interweaving bundles of ovoid or spindle cells without atypia.

Mesothelioma of the atrioventricular node is another benign mesothelioma, however, it is rarely occurs (only 50 cases that reported), usually minute or even microscopic.P this mesothelioma is “the smallest one that can cause death,” since it can cause partial or complete nodal heart blocks and/or sudden death are the major consequences.

Two thirds of mesothelioma of the atrioventricular occurred in females, and have a large age range based attack from an 8-month-old fetus to an 86-year-old woman. Adenomatoid tumors are benign mesothelioma arising in or near the male or female genital tract organs, although occasionally more distantly in the peritoneum.

Benign multi-cystic peritoneal mesothelioma affects mainly young females and produces cysts of variable size and number lined by a single layer of benign mesothelial cells. The major differential diagnoses are lymphangioma and ovarian cancer of low malignant potential. The disease follows a benign course and is compatible with a normal life expectancy, requiring, occasionally, partial excision or decompression for relief of pain or other symptoms. The malignant potential is exceptional.

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Main Article - Pleural Mesothelioma